Betaxolol


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult: PO HTN Initial: 10 mg once daily, may increase to 20 mg/day after 1-2 wk if needed. Ophth Ocular HTN; Open-angle glaucoma As 0.25% or 0.5% drop: Instill 1 drop bid.
Administration
May be taken with or without food.
Contraindications
Sick sinus syndrome, severe bradycardia, cardiogenic shock, uncontrolled cardiac failure, 2nd or 3rd degree AV block, severe bronchial asthma, severe COPD, metabolic acidosis, untreated phaeochromocytoma, severe peripheral arterial disease.
Special Precautions
Patients w/ bronchospastic disease, DM, corneal disease. May mask signs of hyperthyroidism and acute hypoglycaemia. Avoid abrupt withdrawal as it may exacerbate angina, MI, ventricular arrhythmias and precipitate thyroid storm. Patients undergoing surgery involving general anaesth. Renal and hepatic impairment. Pregnancy and lactation. Monitoring Parameters Monitor BP, pulse and baseline renal function.
Adverse Reactions
Eye discomfort (stinging and burning), bradycardia, palpitation, chest pain, oedema, insomnia, fatigue, lethargy, nausea, dyspepsia, diarrhoea, arthralgia, paraesthesia, dyspnoea, pharyngitis, antinuclear antibody positive, cold extremities.
Drug Interactions
Increased risk of bradycardia w/ digitalis glycosides. May cause mydriasis w/ epinephrine. Potential additive effect w/ oral Ca channel blockers, β-adrenergic blockers, antiarrhythmics (including amiodarone), parasympathomimetics, guanethidine. Increased risk of myocardial depression and hypotension w/ peripheral muscle relaxants (e.g. tubocurarine).
ATC Classification
S01ED02 - betaxolol ; Belongs to the class of beta blocking agents. Used in the treatment of glaucoma.
C07AB05 - betaxolol ; Belongs to the class of selective beta-blocking agents. Used in the treatment of cardiovascular diseases.
Disclaimer: This information is independently developed by CIMS based on betaxolol from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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