Buclizine


Full Generic Medicine Info
Dosage/Direction for Use

Oral
Prophylaxis of motion sickness
Adult: As hydrochloride: 25 or 50 mg given 30 min before travelling, repeated after 4-6 hr, if necessary.

Oral
Migraine
Adult: As hydrochloride: 12.5 mg taken as soon as symptoms arise.
Child: 10-14 yr: 6.25 mg at the start of the symptoms. >14 yr: follow adult dose.

Oral
Nausea and vomiting
Adult: As hydrochloride: 25 or 50 mg tid.

Oral
Pruritic skin disorders
Adult: As hydrochloride: 25-50 mg daily.
Administration
Should be taken with food. Take w/in 30 min before meals.
Contraindications
Hypersensitivity; neonates.
Special Precautions
Driving or operating machinery; open-angle glaucoma; urinary retention; prostatic hyperplasia, pyloroduodenal obstruction, epilepsy; renal and hepatic impairment; pregnancy.
Adverse Reactions
Drowsiness, dizziness, incoordination; blurred vision; urinary retention; vomiting; rash; dry mouth; headache, nausea, epigastric pain, wt gain and diarrhoea.
Action
Buclizine is a piperazine antihistamine with antimuscarinic and moderate sedative properties. It is used mainly for its antiemetic action and in the treatment of migraine in combination with analgesics.
ATC Classification
R06AE01 - buclizine ; Belongs to the class of piperazine derivatives used as systemic antihistamines.
Disclaimer: This information is independently developed by CIMS based on buclizine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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