Calcium carbonate


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult: PO Hypocalcaemia and calcium deficiency states 0.5-4 g/day in 1-3 divided doses. Hyperacidity 0.5-3 g as symptoms occur. Max: 7.5 g/day for up to 2 weeks. Hyperphosphataemia in patients with chronic renal failure 3-7 g/day in divided doses; adjust according to patient's serum phosphate level.
Administration
Calcium carbonate + colecalciferol + menaquinone k7: Should be taken with food.
Colecalciferol: May be taken with or without food. Take w/ meals for better absorption. Avoid taking w/ large amount of fibre-rich food.
Contraindications
Patients with hypercalcaemia resulting from myeloma, bone metastases, or other malignant bone disease, sarcoidosis, primary hyperparathyroidism, vitamin D overdosage, long term immobilisation accompanied by hypercalcaemia and/or hypercalciuria; severe hypercalciuria, calci-lithiasis, and renal calculi. Severe renal failure untreated by renal dialysis.
Special Precautions
Patients with achlorhydria, hypoparathyroid disease, history of nephrolithiasis, mild hypercalciuria. Mild to moderate renal impairment. Pregnancy and lactation. Monitoring Parameters Monitor serum and urinary Ca levels, kidney function, and Ca excretion.
Adverse Reactions
Significant: Constipation, flatulence. Endocrine disorders: Hypercalcaemia, hypophosphataemia, milk-alkali syndrome. Gastrointestinal disorders: Abdominal pain, diarrhoea, hyperacidity (acid rebound), nausea, vomiting, xerostomia. Metabolism and nutrition disorders: Anorexia. Nervous system disorders: Headache.
Drug Interactions
Increased risk of hypercalcaemia and metabolic alkalosis in patients taking thiazide diuretics. Enhanced arrythmogenic effect for patients taking cardiac glycosides (e.g. digoxin). Reduces absorption of thyroxine, bisphosphonates, Na fluoride, antibiotics (quinolone and tetracycline), and Fe. Systemic corticosteroids may reduce Ca absorption.
ATC Classification
A12AA04 - calcium carbonate ; Belongs to the class of calcium-containing preparations. Used as dietary supplements.
A02AC01 - calcium carbonate ; Belongs to the class of calcium-containing antacids.
Disclaimer: This information is independently developed by CIMS based on calcium carbonate from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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