Carbetocin


Generic Medicine Info
Contraindications
Pre-eclampsia/eclampsia, severe CV disease, epilepsy. Admin prior to delivery, including induction of labour (elective or medical). Hepatic and renal impairment. Pregnancy.
Special Precautions
Patient w/ asthma, migraine, CV disease, hyponatraemia. Lactation. Monitoring Parameters Monitor for persistent postpartum bleeding and BP.
Adverse Reactions
Headache, dizziness, tremor, anxiety; tachycardia, hypotension, flushing, sweating; dyspnoea, pruritus; chest and back pain, chills, feeling of warmth; nausea, vomiting, abdominal pain, metallic taste; anaemia.
Drug Interactions
Potentiated effect w/ prostaglandins. Enhanced hypotensive effect w/ inhalational anaesthetics (e.g. halothane). May cause severe HTN w/ vasoconstrictors in conjunction w/ caudal-block anaesthesia. May enhance BP w/ ergot alkaloids (e.g. methylergometrine).
ATC Classification
H01BB03 - carbetocin ; Belongs to the class of oxytocin and analogues. Used in posterior pituitary lobe hormone preparations.
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