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Contraindications
Patients treated with MAOI or stopped MAOI within the last 2 wk; moderate or severe hypertension; pulmonary hypertension; structural cardiac abnormalities or advanced arteriosclerosis; adrenal tumour; hyperthyroidism or hyperexcitability; coronary thrombosis; closed-angle glaucoma; pregnancy.
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Special Precautions
Heart disease, mild hypertension, CHF or angina of effort; prostate hyperplasia; patients with history of drug or alcohol abuse; DM; psychotic patients; renal disease. Growth retardation may occur in children.
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Adverse Reactions
Headache, tachycardia, precordial pain, giddiness, restlessness or insomnia; dry mouth and thrist, nausea, vomiting, sweating; difficulty in micturition; muscular weakness and tremors; tolerance and /or dependence may occur.
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Drug Interactions
Reduced effect of guanethidine. Increased risk of arrhythmia in patients treated with digitalis due to its sympathomimetic effects. Increased risk of arrhythmia with choroform, cyclopropane, halothane or other halogenated anesthetics. The effect of cathine may be reduced/enhanced by tricyclic anti-depressants.
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CIMS Class
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ATC Classification
A08AA07 - cathine ; Belongs to the class of centrally acting antiobesity products. Used in the treatment of obesity.
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