Generic Medicine Info
May be taken with or without food.
Hypersensitivity to cefaclor or to other cephalosporins.
Special Precautions
Hypersensitivity to penicillins. History of GI disease. Renal impairment. Pregnancy and lactation. Monitoring Parameters Monitor renal function. Observe for signs of anaphylaxis during 1st dose.
Adverse Reactions
GI effects (e.g. diarrhoea, nausea, vomiting), headache, rash. Rarely, serum sickness-like reactions consisting of erythema multiforme or maculopapular pruritic rash or urticaria accompanied by arthritis, arthralgia, irritability and fever.
Potentially Fatal: Severe hypersensitivity reactions (e.g. Stevens-Johnson syndrome, toxic epidermal necrolysis and anaphylaxis), pseudomembranous colitis.
Drug Interactions
May enhance the nephrotoxic effect of aminoglycosides. May diminish the therapeutic effect of BCG, typhoid vaccine and Na picosulfate. Concomitant use w/ warfarin may increase prothrombin time. Probenecid inhibits renal excretion of cefaclor.
CIMS Class
ATC Classification
J01DC04 - cefaclor ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.
Disclaimer: This information is independently developed by CIMS based on cefaclor from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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