Cerivastatin sodium


Concise Prescribing Info
Indications/Uses
Hypercholesterolaemia.
Dosage/Direction for Use
Adult: PO Initial: 100 mcg once daily in the evening, may increase by increments of 100 mcg at intervals of at least 4 wk. Max: 300 mcg/day.
Contraindications
Active liver disease or unexplained persistent elevated serum transaminase levels; porphyria. Pregnancy.
Special Precautions
Severe renal impairment. Monitoring Parameters Monitor LFT.
Adverse Reactions
GI disturbances, dysgeusia; headache, dizziness, insomnia; rashes; blurred vision. Rarely, HTN; somnolence. oedema, fever, abnormal laboratory test, angina pectoris, anorexia, colitis, duodenal ulcer, GI haemorrhage, anaemia, leucopaenia, increased amylase, myopathy, hyperkinesia, paralysis, corneal ulcer, abnormal renal function.
Potentially Fatal: Hepatitis, pancreatitis, severe rhabdomyolysis.
Drug Interactions
May increase risk of rhabdomyolysis w/ HIV protease inhibitors. May increase risk of myopathy w/ immunosuppressants, fibric acid derivatives, nicotinic acid. Increased bleeding risk w/ anticoagulants. Increased plasma levels w/ mibefradil.
Disclaimer: This information is independently developed by CIMS based on cerivastatin sodium from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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