Chloral hydrate


Generic Medicine Info
Contraindications
Severe cardiac disease, acute porphyria, gastritis, oesophagitis, gastric/duodenal ulcer; obstructive sleep apnoea in childn. Marked hepatic or renal impairment. Lactation.
Special Precautions
Patient w/ resp insufficiency, sleep apnoea, depression, suicidal tendency, history of drug or alcohol abuse. Childn, elderly. Pregnancy. Patient Counselling Avoid contact w/ skin or mucous membranes. Avoid prolonged use or abrupt withdrawal. This drug may cause drowsiness, if affected, do not drive or operate machinery. Monitoring Parameters Monitor vital signs, oxygen saturation, and BP.
Adverse Reactions
Significant: Gastric irritation (e.g. nausea, vomiting, diarrhoea), abdominal distention, flatulence, tolerance, dependence. Nervous: Drowsiness, lightheadedness, headache, paradoxical excitement, hallucination, nightmares, confusion, ataxia. GI: Gastritis, unpleasant taste. Genitourinary: Ketonuria, parenchymatous renal injury. Dermatologic: Erythema multiforme, Stevens-Johnson syndrome.
Potentially Fatal: Delirium tremens.
Drug Interactions
Enhanced sedative effect w/ opiates, barbiturates, TCAs, antipsychotics, antihistamines, and other sedatives. May cause hot flushes, sweating, and HTN w/ IV furosemide. May cause delirium w/ anticholinergics or psychotropics. May produce a transient increase in hypoprothrombinemic response to warfarin.
ATC Classification
N05CC01 - chloral hydrate ; Belongs to the class of aldehydes and derivatives. Used as hypnotics and sedatives.
Disclaimer: This information is independently developed by CIMS based on chloral hydrate from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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