Chlorzoxazone: Indication, Dosage, Side Effect, Precaution

Generic Medicine Info Full Generic Medicine Info

Dosage/Direction for Use Administration Contraindications Special Precautions Adverse Reactions Overdosage Drug Interactions Food Interaction Action Storage CIMS Class ATC Classification

This information is not country-specific. Please refer to the India prescribing information.

Generic Medicine Info

Administration

Should be taken with food.

Contraindications

Hepatic impairment.

Special Precautions

Patient w/ history of liver disease, porphyria. Pregnancy. Patient Counselling This drug may cause CNS depression, if affected, do not drive or operate machinery. This drug may cause orange or reddish-purple urine colouration. Monitoring Parameters Monitor LFT periodically; assess signs or symptoms of hepatotoxicity.

Adverse Reactions

Significant: Elevated liver enzymes (i.e. ALT, AST, bilirubin, alkaline phosphatase). Nervous: Drowsiness, dizziness, headache, light-headedness, malaise, overstimulation. GI: Anorexia, nausea, vomiting, heartburn, abdominal distress, constipation, diarrhoea. Hepatic Jaundice. Genitourinary: Urine discolouration. Dermatologic: Rashes, petechiae, ecchymosis, urticaria, pruritus.
Potentially Fatal: Rarely, hepatocellular toxicity.

Drug Interactions

Enhanced CNS effect w/ other CNS depressants. Increased serum concentration w/ disulfiram, isoniazid.

CIMS Class

Muscle Relaxants

ATC Classification

M03BB03 - chlorzoxazone ; Belongs to the class of oxazol, thiazine, and triazine derivative agents. Used as centrally-acting muscle relaxants.

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