Choriogonadotropin alfa


Generic Medicine Info
Contraindications
Primary ovarian failure, uncontrolled thyroid or adrenal function; abnormal uterine bleeding; ovarian enlargement or cyst of unknown origin; tumours of the hypothalamus, pituitary gland, and uterus; sex hormone dependent tumours of the reproductive tract and accessory organs; ovarian, uterine, or mammary carcinoma. Post-menopausal women. Pregnancy (including ectopic pregnancy in previous 3 mth).
Special Precautions
Patient w/ active or history of thromboembolic events, patient undergoing ovarian stimulation or ovulation induction. Lactation. Monitoring Parameters Monitor oestradiol levels and perform ultrasound to assess follicular development, size, and number. Perform sonographic visualisation to monitor ovulation by determining basal body temp, serum progestin level, and menstruation.
Adverse Reactions
Significant: Ovarian hyperstimulation syndrome (OHSS), multiple births, ovarian enlargement, arterial thromboembolism. Nervous: Headache, tiredness, mood changes, depression, restlessness. GI: Nausea, vomiting, abdominal pain and distension. Genitourinary: Ovarian cysts, ectopic pregnancy. Others: Pain, burning, inflammation, and brusing at inj site, postoperative pain.
ATC Classification
G03GA08 - choriogonadotropin alfa ; Belongs to the class of gonadotropins. Used as ovulation stimulants.
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