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Indications/Uses
Listed in Dosage.
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Dosage/Direction for Use
Adult: Inhalation Asthma As metered-dose aerosol (80 or 160 mcg/actuation): 160 mcg as a single or in 2 divided doses daily. Maintenance: 80 mcg once daily. Severe asthma: 320 mcg bid. Nasal Perennial and seasonal allergic rhinitis As spray (50 mcg/actuation): 200 mcg/day, given as 2 sprays in each nostril once daily.
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Contraindications
Primary treatment of severe acute asthma or status asthmaticus where intensive measures are needed.
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Special Precautions
Patient w/ active or quiescent pulmonary TB, fungal, viral or bacterial infections, unless adequately treated. Avoid abrupt withdrawal. Severe hepatic impairment. Pregnancy and lactation. Monitoring Parameters Monitor height of childn and adolescents on long term treatment w/ inhaled corticosteroids; signs/symptoms of adrenal insufficiency, ocular effects (e.g. cataracts, glaucoma).
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Adverse Reactions
Bad taste, paradoxical bronchospasm, rash and eczema, application site reactions, cough, nausea, vomiting, headache, dysphonia, oral fungal infections. Systemic effects after prolonged use (e.g. Cushing's syndrome, Cushingoid features, adrenal suppression, growth retardation in childn and adolescents, bone mineral density decrease, cataract, glaucoma). Rarely, immediate hypersensitivity reactions or contact dermatitis (nasal).
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Drug Interactions
Increased risk of systemic side effects w/ concomitant ketoconazole, itraconazole, ritonavir, nelfinavir or other potent CYP3A4 inhibitors.
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ATC Classification
R01AD13 - ciclesonide ; Belongs to the class of topical corticosteroids used for prophylaxis and treatment of allergic rhinitis.
R03BA08 - ciclesonide ; Belongs to the class of other inhalants used in the treatment of obstructive airway diseases, glucocorticoids. |
