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Contraindications
Prostatic enlargement, paralytic ileus or pyloric stenosis.
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Special Precautions
Caution when used in patients with diarrhoea or fever. Thyrotoxicosis, heart failure and in cardiac surgery. Children, elderly. Not advisable for use in angle-closure glaucoma.
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Adverse Reactions
Mouth dryness, reduced bronchial secretions, pupil dilatation with loss of accommodation and photophobia. Skin flushing and dryness, transient bradycardia followed by tachycardia, with palpitations and arrhythmias, and micturition difficulty, as well as reduction in tone and motility of the GI tract resulting in constipation.
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Drug Interactions
Effects may be enhanced when used with drugs with antimuscarinic properties e.g. amantadine, some antihistamines, phenothiazines and TCAs. May antagonise the GI effects of cisapride, domperidone and metoclopramide.
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CIMS Class
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ATC Classification
A03BB05 - cimetropium bromide ; Belongs to the class of belladonna alkaloids, semisynthetic, quaternary ammonium compounds. Used in the treatment of functional gastrointestinal disorders.
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