Clobetasone


Generic Medicine Info
Contraindications
Untreated cutaneous infections, rosacea, acne vulgaris, perioral dermatitis, pruritus w/o inflammation.
Special Precautions
Childn. Pregnancy and lactation. Patient Counselling Avoid contact w/ the face, eyes, scalp, genitals, groin, axilla, or between toes. Avoid use w/ occlusive dressing. Avoid abrupt withdrawal. Monitoring Parameters Monitor for adrenal insufficiency and hypothalamic-pituitary-adrenal (HPA) axis suppression.
Adverse Reactions
Significant: Contact dermatitis, skin irritation. Rarely, HPA axis suppression or hypercorticism (i.e. Cushing's syndrome, hyperglycaemia, glycosuria). CV: HTN. Endocrine: Wt gain/obesity. Musculoskeletal: Osteoporosis. Ophthalmologic: Increased intraocular pressure, glaucoma, cataract. Dermatologic: Exacerbation of eczema, urticaria, rash, pruritus, erythema, skin atrophy, acne, hypertrichosis, striae atrophicae, telangiectasia, mild depigmentation, perioral dermatitis.
Drug Interactions
Increased systemic exposure w/ CYP3A4 enzyme inhibitors (e.g. itraconazole, ritonavir). May diminish the antineoplastic effect of aldesleukin. May potentiate the hyperglycaemic effect of ceritinib. May diminish the therapeutic effect of corticorelin and hyaluronidase. May enhance the adverse/toxic effects of deferasirox.
ATC Classification
D07AB01 - clobetasone ; Belongs to the class of moderately potent (group II) corticosteroids. Used in the treatment of dermatological diseases.
S01BA09 - clobetasone ; Belongs to the class of corticosteroids. Used in the treatment of inflammation of the eye.
Disclaimer: This information is independently developed by CIMS based on clobetasone from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in