Clonazepam


Generic Medicine Info
Administration
May be taken with or without food.
Contraindications
Patient w/ acute angle closure glaucoma, acute pulmonary insufficiency, severe resp insufficiency, myasthenia gravis, sleep apnoea syndrome.
Special Precautions
Patient w/ open angle glaucoma, chronic pulmonary insufficiency, porphyria, spinal or cerebellar ataxia, history of alcohol or drug addiction, and depression and/or suicide attempts. Increased risk of suicidal behaviour and ideation. Avoid abrupt withdrawal. Renal and hepatic impairment. Elderly or debilitated patient. Pregnancy and lactation. Patient Counselling May impair ability to drive or operate machinery. Monitoring Parameters Monitor signs of suicidal ideation, resp depression and BP.
Adverse Reactions
Drowsiness or sedation, fatigue, muscular hypotonia, behavioural disturbances including aggressiveness, agitation, hyperkinesis and irritability; coordination disturbances, dizziness, vertigo, anorexia, visual disturbances, libido changes; rhinorrhoea, chest congestion and shortness of breath; skin rash, hair loss, hirsutism, and ankle and facial oedema; diarrhoea, constipation, wt gain or loss, abnormal thirst, encopresis, gastritis, increased or decreased appetite, dyspepsia, nausea, coated tongue, dry mouth, sore gums; nocturia, dysuria, enuresis, urinary retention. Salivary or bronchial hypersecretion leading to resp problems (childn). Rarely, abnormal skin pigmentation.
Drug Interactions
Additive depressant effect w/ TCAs, MAOIs, sedative and hypnotics, barbiturates, anxiolytics, antipsychotics, opiate agonists. May increase serum phenytoin levels.
ATC Classification
N03AE01 - clonazepam ; Belongs to the class of benzodiazepine derivatives antiepileptic.
Disclaimer: This information is independently developed by CIMS based on clonazepam from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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