Generic Medicine Info
Foetal distress, significant cephalopelvic disproportion, unfavorable presentation of the fetus, excess uterine distention; parity >4; elderly multiparae; previous uterine surgery; severe toxemia; amniotic fluid embolism; hypertonic uterine contractions; placenta praevia; cord presentation or prolapse; mechanical obstruction to delivery; predisposition to uterine rupture.
Special Precautions
Borderline cephalopelvic disproportion; patients >35 yr. Monitor fetal heart rate and uterine motility. Do not employ for prolonged periods in resistant uterine inertia, severe preeclampsia, severe CV disorders. Discontinue in case of foetal distress or uterine hyperactivity. Risk of water intoxication (high doses over prolonged period). Restrict fluid intake by mouth.
Adverse Reactions
Postpartum bleeding; neonatal jaundice; water retention; acute transient hypotension with flushing and reflex tachycardia (rapid IV).
Potentially Fatal: Death; anaphylactic reactions; fatal afibrinogenaemia; maternal deaths from severe hypertension and subarachnoid haemorrhage.
Drug Interactions
Prostaglandins, anaesthetics. Vasopressor effects of sympathomimetics may be enhanced.
ATC Classification
H01BB01 - demoxytocin ; Belongs to the class of oxytocin and analogues. Used in posterior pituitary lobe hormone preparations.
Disclaimer: This information is independently developed by CIMS based on demoxytocin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by
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