Dextromethorphan


Concise Prescribing Info
Indications/Uses
Cough suppressant.
Dosage/Direction for Use
Adult: PO As dextromethorphan hydrobromide: As conventional preparation: 10-20 mg 4 hourly, or 30 mg 6-8 hourly. As extended-release preparation: 60 mg 12 hourly. Max: 120 mg/day. As loz: Suck not more than 12 loz/day.
Administration
May be taken with or without food.
Contraindications
Asthma, bronchitis, emphysema or other conditions where persistent or chronic cough occurs. Concomitant use or within 14 days of MAOI or SSRI therapy. Children <12 years.
Special Precautions
Patient with history of drug abuse. Children. Treatment with a cough medicine in children (especially under 12 years old) should be considered carefully due to potential risks and limited evidence on efficacy. Pregnancy and lactation. Patient Counselling This drug can cause drowsiness or cognitive function impairment, if affected, do not drive or operate machinery.
Adverse Reactions
Gastrointestinal disorders: Abdominal pain, diarrhoea, gastrointestinal disturbance, nausea, vomiting. Nervous system disorders: Dizziness, drowsiness, convulsion, psychomotor hyperactivity, somnolence, serotonin syndrome, excitement, nervousness. Psychiatric disorders: Insomnia, confusional state. Respiratory, thoracic and mediastinal disorders: Respiratory depression.
Drug Interactions
Additive CNS effect when used with antihistamines, psychotropics and other CNS depressants. Increased toxic effect when used with potent CYP2D6 enzyme inhibitors (e.g. fluoxetine, paroxetine, quinidine, terbinafine).
ATC Classification
R05DA09 - dextromethorphan ; Belongs to the class of opium alkaloids and derivatives. Used as cough suppressant.
Disclaimer: This information is independently developed by CIMS based on dextromethorphan from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
MORE
LESS
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in