Dextromethorphan


Generic Medicine Info
Administration
May be taken with or without food.
Contraindications
Acute asthma attack, respiratory insufficiency or respiratory depression; chronic cough that lasts as occurs with smoking, emphysema, or cough that occurs with too much phlegm (mucus). Individuals at risk of developing respiratory failure (e.g. COPD, pneumonia). Hepatic impairment. Concomitant use with MAOIs (and within 14 days of stopping treatment), SSRIs, other antidepressants (e.g. TCAs), or medicines for Parkinson's disease.
Special Precautions
Patient with history of asthma, current or history of substance misuse disorder (including alcohol abuse) or mental health disorder (e.g. major depression). CYP2D6 poor metabolisers. Debilitated patients. Children (especially atopic children). Treatment with a cough medicine in children (particularly under 12 years of age) should be considered carefully due to potential risks and limited evidence on efficacy. Pregnancy and lactation. Patient Counselling This drug may cause dizziness or drowsiness, if affected, do not drive or operate machinery.
Adverse Reactions
Significant: Drug dependence (particularly with prolonged use). Gastrointestinal disorders: Diarrhoea, gastrointestinal distress, stomach pain, nausea, vomiting. Nervous system disorders: Dizziness, drowsiness, convulsions. Psychiatric disorders: Excitation, mental confusion, nervousness, restlessness. Respiratory, thoracic and mediastinal disorders: Respiratory depression. Skin and subcutaneous tissue disorders: Rash.
Drug Interactions
Serotonin syndrome may occur with concomitant use of MAOIs (and within 14 days of stopping MAOI treatment), SSRIs (e.g. fluoxetine), TCAs (e.g. clomipramine, imipramine) or medicines for Parkinson's disease.
CIMS Class
Cough & Cold Preparations
ATC Classification
R05DA09 - dextromethorphan ; Belongs to the class of opium alkaloids and derivatives. Used as cough suppressant.
Disclaimer: This information is independently developed by CIMS based on dextromethorphan from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2023 CIMS. All rights reserved. Powered by CIMSAsia.com
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