Generic Medicine Info
Acute or history of pelvic inflammatory disease, vag infections or cervicitis, placenta praevia or unexplained vag bleeding, history of major uterine surgery or caesarean section, cephalopelvic disproportion, foetal malpresentation, foetal distress, grand multiparae, history of traumatic delivery, ruptured membranes. Active cardiac, pulmonary, renal or hepatic disease.
Special Precautions
Patient w/ compromised uteri, asthma, glaucoma, raised intraocular pressure, HTN or CV disease, epilepsy, gestational diabetes, hypothyroidism. Compromised cardiac, hepatic, or renal function. Monitoring Parameters Monitor foetal heart rate, uterine activity, progression of cervical dilation and effacement (gel, insert); confirmation of foetal death (supp).
Adverse Reactions
Significant: Rarely, disseminated intravascular coagulation (DIC). CV: HTN. GI: Diarrhoea, nausea, vomiting. Resp: Asthma, bronchospasm. Genitourinary: Uterine hypertonus, uterine rupture, abruptio placenta, pulmonary amniotic fluid embolism, rapid cervical dilatation, vag warmth, irritation, and pain. Musculoskeletal: Back pain. Dermatologic: Rash. Immunologic: Anaphylactoid reactions including shock. Others: Fever.
Potentially Fatal: Cardiac arrest.
Drug Interactions
Potentiates the uterotonic effect of oxytocic drugs.
ATC Classification
G02AD02 - dinoprostone ; Belongs to the class of prostaglandins. Used to induce abortion or augment labour and to minimize blood loss from the placental site.
Disclaimer: This information is independently developed by CIMS based on dinoprostone from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in