Docusate sodium


Generic Medicine Info
Contraindications
Presence of abdominal pain which is not constipation-related, nausea and vomiting, intestinal obstruction (oral, rectal); rectocolitis, ileus, inflammatory bowel disease, anal bleeding, haemorrhoids or anal fissures (rectal). Otic: Eardrum perforation, ear inflammation or pain. Oral: Concomitant use with mineral oil laxatives (e.g. liquid paraffin).
Special Precautions
Avoid prolonged use. Children. Pregnancy and lactation. Monitoring Parameters Rectal: Perform rectal exams periodically in patients with impaired rectal function, particularly loss of sensation.
Adverse Reactions
Significant: Atonic non-functioning colon and hypokalaemia (prolonged use); ear pain or inflammation (otic). Gastrointestinal disorders: Burning sensation in the mouth and throat (oral solution); anorectal pain or bleeding (rectal). Rarely, diarrhoea, nausea, abdominal cramps. General disorders and administration site conditions: Rarely, application site reactions including transient stinging or irritation (otic). Skin and subcutaneous tissue disorders: Rash, pruritus; contact dermatitis, allergic skin reactions (otic).
Drug Interactions
Increased absorption of anthraquinone derivative laxatives.
ATC Classification
A06AA02 - docusate sodium ; Belongs to the class of softeners, emollients laxatives.
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