Doxofylline


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult: PO Reversible airways obstruction; COPD 400 mg bid-tid.
Contraindications
Acute MI, hypotension. Lactation.
Special Precautions
Patients with cardiac disease (e.g. cardiac arrhythmias, angina pectoris, CHF, acute myocardial injury, hypertension), peptic ulcer, hyperthyroidism, hypoxemia, chronic cor pulmonale, convulsive disorder. Hepatic and renal impairment. Children and elderly. Pregnancy.
Adverse Reactions
Cardiac disorders: Tachycardia, palpitation, extrasystole. Metabolism and nutrition disorders: Hyperglycaemia. Gastrointestinal disorders: Nausea, vomiting, abdominal pain, epigastric distress. General disorders and administration site conditions: Irritability. Nervous system disorders: Headache, nervousness, dizziness. Psychiatric disorders: Insomnia, nervousness. Renal and urinary disorders: Albuminuria.
Drug Interactions
Decreased xanthine clearance with cimetidine, allopurinol, propranolol, antibiotics (e.g. erythromycin, lincomycin, ciprofloxacin) and anti-flu vaccine. Increased xanthine clearance with anticonvulsants (e.g. phenytoin). May potentiate hypokalaemia with β-2 agonist.
ATC Classification
R03DA11 - doxofylline ; Belongs to the class of xanthines. Used in the systemic treatment of obstructive airway diseases.
Disclaimer: This information is independently developed by CIMS based on doxofylline from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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