Doxylamine


Generic Medicine Info
Administration
Should be taken with food. Take w/ food or milk.
Contraindications
Lactation.
Special Precautions
Patient w/ increased intraocular pressure/glaucoma, urinary retention, prostate enlargement, pyloroduodenal obstruction, thyroid dysfunction, resp disease, epilepsy or severe CV disorder (e.g. HTN, ischaemic heart disease). Pregnancy. Patient Counselling This drug may cause drowsiness, if affected, do not drive or operate machinery.
Adverse Reactions
CNS depression, stimulation (e.g. insomnia, nervousness, euphoria, irritability, tremors, nightmares, hallucinations, convulsions); headache, lack of coordination, dizziness, psychomotor impairment, constipation, nausea, vomiting, diarrhoea, increased gastric reflux, epigastric pain, thickened resp tract secretions, dry mouth, palpitations, arrhythmias, blurred vision, urinary retention, blood disorders, hypotension, tinnitus, paraesthesia, hypersensitivity reactions.
B FDA Pregnancy Category A applies to doxylamine succinate w/ pyridoxine hydrochloride.
Drug Interactions
Additive effect when administered w/ other CNS depressants (e.g. opioids analgesics, neuroleptics, hypnotics, other psychotherapeutic drugs). Antimuscarinic effects may be enhanced by MAOIs. May decrease emetic response to apomorphine. Additive antimuscarinic effects w/ other antimuscarinic drugs (e.g. atropine, TCAs).
CIMS Class
Antihistamines & Antiallergics / Hypnotics & Sedatives
ATC Classification
R06AA09 - doxylamine ; Belongs to the class of aminoalkyl ethers used as systemic antihistamines.
Disclaimer: This information is independently developed by CIMS based on doxylamine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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