Enalapril + hydrochlorothiazide

Generic Medicine Info
May be taken with or without food.
Hypersensitivity, anuria, aortic stenosis, outflow obstruction, hepatic cirrhosis.
Special Precautions
Renal impairment, anaesthesia, concomitant K supplements and K - sparing diuretics, hypovolemic patients pregnancy, lactation.
Adverse Reactions
Syncope, chest pain, abdominal pain, orthostatic hypotension, palpitation, tachycardia, GI symptoms, insomnia, nervousness, paresthesia, vertigo, skin rash, dyspnoea, gout, arthralgia, tinnitus, decreased libido, cough.
Potentially Fatal: NA.
Drug Interactions
Significant increase in serum K levels with K supplements and K sparing diuretics. Lithium toxicity in patients receiving lithium concomitantly. Alcohol, barbiturates, narcotics potentiate orthostatic hypotension. Dosage adjustment of antidiabetic drugs needed. Potentiation of action of other antihypertensives, corticosteroids, ACTH.
CIMS Class
ACE Inhibitors/Direct Renin Inhibitors / Diuretics
ATC Classification
C03AA03 - hydrochlorothiazide ; Belongs to the class of low-ceiling thiazide diuretics.
C09AA02 - enalapril ; Belongs to the class of ACE inhibitors. Used in the treatment of cardiovascular disease.
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