Enalapril + hydrochlorothiazide


Generic Medicine Info
Administration
May be taken with or without food.
Contraindications
Hypersensitivity, anuria, aortic stenosis, outflow obstruction, hepatic cirrhosis.
Special Precautions
Renal impairment, anaesthesia, concomitant K supplements and K - sparing diuretics, hypovolemic patients pregnancy, lactation.
Adverse Reactions
Syncope, chest pain, abdominal pain, orthostatic hypotension, palpitation, tachycardia, GI symptoms, insomnia, nervousness, paresthesia, vertigo, skin rash, dyspnoea, gout, arthralgia, tinnitus, decreased libido, cough.
Potentially Fatal: NA.
Drug Interactions
Significant increase in serum K levels with K supplements and K sparing diuretics. Lithium toxicity in patients receiving lithium concomitantly. Alcohol, barbiturates, narcotics potentiate orthostatic hypotension. Dosage adjustment of antidiabetic drugs needed. Potentiation of action of other antihypertensives, corticosteroids, ACTH.
CIMS Class
ACE Inhibitors/Direct Renin Inhibitors / Diuretics
ATC Classification
C03AA03 - hydrochlorothiazide ; Belongs to the class of low-ceiling thiazide diuretics.
C09AA02 - enalapril ; Belongs to the class of ACE inhibitors. Used in the treatment of cardiovascular disease.
Disclaimer: This information is independently developed by CIMS based on enalapril + hydrochlorothiazide from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 CIMS. All rights reserved. Powered by CIMSAsia.com
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