Ferrous gluconate


Generic Medicine Info
Administration
Should be taken on an empty stomach. Best taken on an empty stomach. May be taken w/ meals to reduce GI discomfort.
Contraindications
Haemochromatosis, haemosiderosis, haemoglobinuria, anaemias not caused by Fe deficiency (e.g. thalassaemia), active peptic ulcer, regional enteritis, ulcerative colitis, alcoholism, hepatitis. Patients receiving repeated blood transfusions or parenteral Fe therapy.
Special Precautions
Patient w/ intestinal strictures and diverticular disease, haemolytic anaemia, Fe absorption disorders. Childn. Pregnancy and lactation. Patient Counselling This drug may cause black discolouration of the stool. Monitoring Parameters Monitor serum Fe, total Fe binding capacity, Hb, and reticulocyte count.
Adverse Reactions
GI: GI discomfort, anorexia, nausea, vomiting, heartburn, constipation or diarrhroea, faecal impaction, dark stools, dental discolouration. Genitourinary: Urine discolouration. Dermatologic: Allergic reactions, contact dermatitis.
Drug Interactions
May form a chelate w/ acetohydroxamic acid, resulting in reduced absorption of both drugs. Toxic compounds may be formed w/ concomitant use of dimercaprol. Decreased absorption w/ antacids containing Ca salts, carbonates or Mg trisilicate, and other drugs containing bicarbonates, carbonates, oxalates or phosphates due to formation of less soluble or insoluble complexes. Reduced absorption w/ trientine, cholestyramine, tetracyclines, Zn, PPIs. Increased absorption w/ ascorbic and succinic acid. Haematologic response may be impaired when used w/ vit E. Antagonises the hypotensive effect of methyldopa. May reduce the absorption of penicillamine, bisphosphonates, fluoroquinolones, entacapone, mycophenolate, tetracyclines, Zn, levothyroxine, levodopa, carbidopa, nalidixic acid, eltrombopag. Neomycin may alter the absorption of Fe. Oral chloramphenicol delays plasma Fe clearance, incorporation into RBC and interferes w/ erythropoiesis.
ATC Classification
B03AD05 - ferrous gluconate
B03AA03 - ferrous gluconate ; Belongs to the class of oral iron bivalent preparations. Used in the treatment of anemia.
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