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Administration
May be taken with or without food.
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Contraindications
History of depression, pre-existing symptoms of Parkinson's disease, other extrapyramidal disorders.
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Special Precautions
Hepatic impairment. Elderly. Pregnancy and lactation. Patient Counselling This drug may cause somnolence, if affected, do not drive or operate machinery. Monitoring Parameters Monitor for extrapyramidal, depressive, and fatigue symptoms.
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Adverse Reactions
Significant: Depression, increased serum prolactin, menstrual irregularities, extrapyramidal symptoms. Rarely: progressive fatigue, galactorrhoea.
Gastrointestinal disorders: Nausea, vomiting, constipation, stomach pain.
Investigations: Weight gain.
Metabolism and nutrition disorders: Increased appetite.
Musculoskeletal and connective tissue disorders: Myalgia.
Nervous system disorders: Drowsiness, somnolence.
Psychiatric disorders: Insomnia.
Respiratory, thoracic and mediastinal disorders: Rhinitis.
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Drug Interactions
Increases sedative effect with hypnotics and tranquillisers. Decreased plasma concentration with phenytoin, carbamazepine.
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CIMS Class
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ATC Classification
N07CA03 - flunarizine ; Belongs to the class of antivertigo preparations.
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