Folic acid


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult: PO Folate-deficient megaloblastic anaemia 5 mg/day for up to 4 months. May increase to 15 mg/day in malabsorption states. Maintenance: 5 mg every 1-7 days. Prophylaxis of neural tube defect in pregnancy 5 mg/day starting 4 weeks before pregnancy and continued through the 1st trimester.IM/IV/SC Folate-deficient megaloblastic anaemia Up to 1 mg/day. Maintenance: 0.4 mg/day.
Administration
May be taken with or without food.
Contraindications
Untreated pernicious anaemia, untreated cobalamin deficiency or other cause of cobalamin deficiency.
Special Precautions
Patients with folate-dependent tumours. Monitoring Parameters Perform cobalamin absorption test for elderly prior to initiation of therapy.
Adverse Reactions
Cardiac disorders: Flushing. Gastrointestinal disorders: Anorexia, nausea, abdominal distention, flatulence. Immune system disorders: Allergic reactions. Nervous system disorders: Malaise. Respiratory, thoracic and mediastinal disorders: Bronchospasm. Skin and subcutaneous tissue disorders: Erythema, pruritus, skin rash, hypersensitivity.
Drug Interactions
May decrease concentration of phenytoin. Decreased absorption with sulfasalazine, and triamterene. Chloramphenicol, methotrexate and co-trimoxazole may interfere with folate metabolism. May enhance efficacy of lithium.
ATC Classification
V04CX02 - folic acid
B03BB01 - folic acid ; Belongs to the class of folic acid and derivatives. Used in the treatment of anemia.
Disclaimer: This information is independently developed by CIMS based on folic acid from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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