Gadopentetic acid

Generic Medicine Info
Hypersensitivity. Acute kidney injury, patients in perioperative liver transplantation period. Severe renal impairment (GFR <30 mL/min/1.73 m2). Neonates <4 week.
Special Precautions
Patient with history of allergic reactions, bronchial asthma, seizure disorders, intracranial lesions. Mild to moderate renal impairment. Children. Pregnancy and lactation. Monitoring Parameters Monitor renal function prior to administration. Monitor for signs and symptoms of hypersensitivity reactions, extravasation, nephrogenic systemic fibrosis (e.g. muscle weakness, rib bone pain).
Adverse Reactions
Significant: Gadolinium retention, extravasation reactions (e.g. thrombosis, skin and soft tissue necrosis). Rarely, seizures. Gastrointestinal disorders: Nausea, vomiting, dysgeusia. Injury, poisoning and procedural complications: Inj site reactions (e.g. pain, oedema, irritation). Nervous system disorders: Headache, dizziness. Skin and subcutaneous tissue disorders: Hot or cold sensation.
Potentially Fatal: Nephrogenic systemic fibrosis. Rarely, hypersensitivity (e.g. anaphylactic reactions).
CIMS Class
ATC Classification
V08CA01 - gadopentetic acid ; Belongs to the class of paramagnetic agents used as magnetic resonance imaging contrast media.
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