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Indications/Uses
Listed in Dosage.
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Dosage/Direction for Use
Adult: Ophthalmic Mydriasis and cycloplegia for refraction As homatropine hydrobromide 2% or 5% solution: Instill 1-2 drops into affected eye(s) immediately before the procedure, repeat after 5-10 minutes if necessary. Uveitis As homatropine hydrobromide 2% or 5% solution: Instill 1-2 drops into affected eye(s) bid or tid, or up to 3-4 hourly as needed.
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Contraindications
Primary glaucoma, narrow anterior chamber angle glaucoma.
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Special Precautions
Patient with keratoconus, down syndrome, brain damage, exposed to high environmental temperature. Children. Pregnancy and lactation. Patient Counselling This drug may cause drowsiness, blurred vision and sensitivity to light, if affected, do not drive or operate machinery. Remove contact lenses prior to ophthalmic administration and reinsert after 15 minutes.
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Adverse Reactions
Significant: Fixed dilated pupil, increased ocular pressure; light sensitivity, hyperthermia.
Eye disorders: Transient stinging, burning sensation, irritation, follicular conjunctivitis, exudates, mydriasis, ocular hyperaemia, vascular congestion, blurred vision.
Gastrointestinal disorders: Dry mouth.
Metabolism and nutrition disorders: Oedema.
Psychiatric disorders: Drowsiness, somnolence.
Skin and subcutaneous tissue disorders: Eczemetoid dermatitis.
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Drug Interactions
Enhanced antimuscarinic effect with amantadine, antihistamines, phenothiazine, antipsychotics, and TCA.
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CIMS Class
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ATC Classification
S01FA05 - homatropine ; Belongs to the class of anticholinergics used as mydriatics and cycloplegics.
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