Generic Medicine Info
Myasthenia gravis, narrow-angle glaucoma, tachycardia, megacolon; hypersensitivity.
Special Precautions
Patient with angina, cardiac failure, (including those who are undergoing cardiac surgery), coronary artery disease, hypertension, open angle glaucoma, pyrexia, thyrotoxicosis; pyloric, intestinal or urinary bladder neck obstruction, paralytic ileus, gastrointestinal tract stenoic lesions, prostatic hypertrophy, urinary retention; history of seizure or psychosis. Renal or hepatic impairment. Children. Pregnancy and lactation. Patient Counselling This drug may cause drowsiness, disorientation, confusion, or blurred vision, if affected, do not drive or operate machinery. Remove transdermal hyoscine before medical scan. Monitoring Parameters Monitor heart rate, urinary output, body temperature, and intraocular pressure.
Adverse Reactions
Significant: Tachyarrhythmias, hypotension, increased intra-ocular pressure, drowsiness, confusional states, visual hallucinations, blurred vision, eye pain, idiosyncratic reactions (e.g. agitation, delusion, acute toxic psychosis), epileptic seizures. Nervous system disorders: Dizziness, headache, equilibrium disturbance, excitement, ataxia, hallucinations, behavioural abnormalities, acute toxic psychosis, agitation, confusion, paranoia, rambling speech, fatigue, migraine, irritability, amnesia, restlessness, sedation. Cardiac disorders: Bradycardia. Gastrointestinal disorders: Nausea, vomiting, hypersalivation, diarrhoea, dry mouth, abdominal cramps, constipation, oesophageal ulceration. General disorders and administration site conditions: Hyperpyrexia. Eye disorders: Mydriasis, cycloplegia, eye pruritus. Musculoskeletal: Muscle weakness. Renal and urinary disorders: Urinary retention, dysuria. Skin and subcutaneous tissue disorders: Flushing, sweating, dry skin, rash, erythema, pruritus, skin burns, contact dermatitis (transdermal).
Potentially Fatal: Anaphylaxis, shock.
Drug Interactions
May decrease the absorption of oral medicines due to decreased gastric motility and delayed gastric emptying. The sedative effect of hyoscine may be enhanced by other CNS depressants. Other drugs with anticholinergic properties (e.g. amantadine, antihistamines) may enhance the effects of hyoscine.
Disclaimer: This information is independently developed by CIMS based on hyoscine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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