Indapamide


Generic Medicine Info
Administration
May be taken with or without food.
Contraindications
Hypersensitivity to sulfonamide-derived drugs. Anuria; severe renal failure, hepatic encephalopathy, severe impairment of liver function, hypokalaemia.
Special Precautions
Patient with electrolyte or fluid disturbances, gout, diabetes mellitus, Addison's disease, SLE. Renal and hepatic impairment. Pregnancy and Lactation. Patient Counselling This medicine may cause photosensitivity reactions, avoid exposure to direct sunlight and UV light. Use protective measures (e.g. applying sunscreen) when going outdoors. Monitoring Parameters Monitor blood pressure, serum electrolytes, uric acid, renal and hepatic function. Assess weight, intake and output reports daily to determine fluid loss.
Adverse Reactions
Significant: Photosensitivity, hypersensitivity reactions, electrolyte imbalance (e.g. hyponatraemia, hypokalaemia, hypochloremic alkalosis, hypomagnesaemia, hypercalcaemia). Cardiac disorders: Arrhythmia, chest pain, palpitations. Ear and labyrinth disorders: Vertigo. Eye disorders: Blurred vision, conjunctivitis Gastrointestinal disorders: Constipation, diarrhoea, dyspepsia, abdominal pain, dry mouth, nausea, vomiting. General disorders and administration site conditions: Fatigue, lethargy, malaise. Investigations: Increased blood glucose, increased blood uric acid, elevated liver enzyme levels. Musculoskeletal and connective tissue disorders: Muscle cramps, muscle spasms, back pain. Nervous system disorders: Dizziness, headache, paresthesia. Psychiatric disorders: Insomnia. Renal and urinary disorders: Nocturia, polyuria. Respiratory, thoracic and mediastinal disorders: Rhinitis, cough, pharyngitis, rhimorrhea, sinusitis. Skin and subcutaneous tissue disorders: Pruritus, maculopapular rash, urticaria.
Drug Interactions
Increased risk of lithium toxicity. Increased risk of hypokalaemia and ventricular arrhythmia with drugs that induce torsades de pointes (e.g. disopyramide, amiodarone, sotalol, chlorpromazine, amisulpride, haloperidol). May enhance toxicity of cardiac glycosides (e.g. digoxin). Diminished antihypertensive effect with NSAIDs. May potentiate the action of other antihypertensive agents.
CIMS Class
Diuretics
ATC Classification
C03BA11 - indapamide ; Belongs to the class of low-ceiling sulfonamide diuretics.
Disclaimer: This information is independently developed by CIMS based on indapamide from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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