Lactulose


Generic Medicine Info
Administration
May be taken with or without food. May be taken w/ meals to reduce GI discomfort. Dilute w/ water, milk, or fruit juice to improve taste.
Contraindications
Galactosaemia, gastrointestinal obstruction or subocclusive syndromes, acute inflammatory bowel disease (e.g. ulcerative colitis, Crohn's disease), digestive perforation or risk of digestive perforation, painful abdominal syndromes of unknown cause, low galactose diet.
Special Precautions
Patients with lactose intolerance, diabetes mellitus, gastro-cardiac syndrome (Roemheld syndrome); undergoing electrocautery procedures during proctoscopy or colonoscopy. Debilitated patients. Children (especially infants) and elderly. Pregnancy and lactation. Patient Counselling Drink sufficient amounts of fluids (1.5-2 L or 6-8 glasses daily). Monitoring Parameters Monitor blood pressure, serum electrolytes, serum ammonia, fluid status and bowel movement patterns.
Adverse Reactions
Significant: Electrolyte imbalance (long-term treatment or excessive doses). Gastrointestinal disorders: Nausea, vomiting, diarrhoea (high doses), flatulence, abdominal cramps, pain, or distension. Metabolism and nutrition disorders: Dehydration.
Drug Interactions
May diminish the therapeutic effect with glutamine. May increase the loss of K induced by thiazides, steroids and amphotericin B. May increase the effects of cardiac glycosides. May reduce desired effect with nonabsorbable antacids, neomycin, or other oral anti-infectives.
ATC Classification
A06AD11 - lactulose ; Belongs to the class of osmotically acting laxatives.
Disclaimer: This information is independently developed by CIMS based on lactulose from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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