Lincomycin


Generic Medicine Info
Administration
Should be taken on an empty stomach. Take w/ full glass of water on an empty stomach 1 hr before or 2 hr after meals.
Contraindications
Hypersensitivity to lincomycin or clindamycin.
Special Precautions
Patient w/ history of GI disease particularly colitis, history of asthma or significant allergies. Severe renal and/or hepatic impairment. Pregnancy and lactation. Monitoring Parameters Periodically perform LFTs, kidney function tests and blood cell counts during prolonged therapy.
Adverse Reactions
Nausea, vomiting, diarrhoea, abdominal pain, tenesmus, glossitis, stomatitis, pruritus ani; rash, vaginitis, leucopenia, neutropenia, agranulocytosis, eosinophilia, thrombocytopaenic purpura; transient increases in serum bilirubin, alkaline phosphatase, and AST, jaundice, headache, myalgia, tinnitus, dizziness, vertigo, azotemia, oliguria, proteinuria, hypotension, syncope; reversible increases in serum creatine kinase (CK) and creatine phosphokinase (CPK); induration, and sterile abscess on inj site w/ IM admin. Rarely, erythema multiforme resembling Stevens-Johnson syndrome, exfoliative and vesiculobullous dermatitis, cardiopulmonary arrest, aplastic anaemia, pancytopenia; thrombophlebitis, erythema, pain and swelling w/ IV admin.
Potentially Fatal: Clostridium difficile-associated diarrhoea and colitis, serious anaphylactoid reactions.
Drug Interactions
May potentiate effects of neuromuscular blocking agents (e.g. pancuronium, tubocurarine). Reduced GI absorption w/ kaolin. May antagonise the effect of erythromycin.
CIMS Class
ATC Classification
J01FF02 - lincomycin ; Belongs to the class of lincosamides. Used in the systemic treatment of infections.
Disclaimer: This information is independently developed by CIMS based on lincomycin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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