Mecobalamin


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult: PO Peripheral neuropathies; Megaloblastic anaemia caused by vitamin B12 deficiency 500 mcg tid. IV/IM Peripheral neuropathies 500 mcg 3 times weekly. IV/IM Megaloblastic anaemia caused by vitamin B12 deficiency 500 mcg 3 times weekly for 2 months. Maintenance therapy: 500 mcg every 1-3 months.
Administration
May be taken with or without food.
Special Precautions
Pregnancy and lactation. Monitoring Parameters Monitor serum K and vitamin B12 levels; haematocrit and reticulocyte counts.
Adverse Reactions
Gastrointestinal disorders: Nausea, vomiting, diarrhoea, abdominal pain. General disorders and administration site conditions: Hot sensation, diaphoresis, pain/induration (IM). Immune system disorder: Rarely, hypersensitivity reaction e.g. rash, dyspnoea. Metabolism and nutrition disorders: Anorexia. Nervous system disorders: Headache.
Drug Interactions
Decreased absorption with aminosalicylic acid, chloramphenicol, colchicine, histamine-2 antagonists, neomycin and proton pump inhibitors (e.g. omeprazole). Decreased serum concentrations with oral contraceptives. Impaired therapeutic response with large and continuous doses of folic acid.
ATC Classification
B03BA05 - mecobalamin ; Belongs to the class of vitamin B12 (cyanocobalamin and analogues). Used in the treatment of anemia.
Disclaimer: This information is independently developed by CIMS based on mecobalamin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 CIMS. All rights reserved. Powered by CIMSAsia.com
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