Full Generic Medicine Info
Dosage/Direction for Use

Pruritic skin disorders, Hypersensitivity reactions
Adult: As 2% cream: Apply sparingly onto affected area(s) 2-3 times daily for up to 3 days.
Child: ≥2 yr Same as adult dose.
Application to eczematous skin conditions or extensively broken skin surfaces.
Special Precautions
Childn. Pregnancy and lactation. Patient Counselling Avoid contact on large areas of skin, broken, sunburnt, cut or grazed skin. This drug may cause somnolence and mild disorientation, if affected, do not drive or operate machinery.
Adverse Reactions
Significant: Rarely, skin sensitisation. Immunologic: Local hypersensitivity reactions.
Mepyramine is an ethylenediamine derived antihistamine w/ anti-pruritic and local analgesic action. It competitively blocks histamine at H1 receptor sites thus inhibiting the effect of histamine in the body.
Absorption: Readily absorbed through the skin.
Metabolism: Metabolised in the liver.
Excretion: Mainly via urine as metabolites.
Topical/Cutaneous: Store below 25°C.
CIMS Class
Topical Antihistamines/Antipruritics
ATC Classification
R06AC01 - mepyramine ; Belongs to the class of substituted ethylene diamines used as systemic antihistamines.
D04AA02 - mepyramine ; Belongs to the class of topical antihistamines used in the treatment of pruritus.
Disclaimer: This information is independently developed by CIMS based on mepyramine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by
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