Metadoxine


Full Prescribing Info
Dosage/Direction for Use

Oral
Acute alcohol intoxication
Adult: 500-1000 mg daily.

Oral

Alcoholic fatty liver
Adult: 1000 mg daily.

Oral

Supportive treatment of acute and chronic liver diseases
Adult: 1000 mg daily.

Parenteral

Acute alcohol intoxication
Adult: 300-600 mg daily IM/IV.

Parenteral

Alcoholic fatty liver
Adult: 300 mg daily IM/IV.

Parenteral

Supportive treatment of acute and chronic liver diseases
Adult: 300 mg daily IM/IV.
Contraindications
Pregnancy and lactation.
Drug Interactions
May reduce effects of levodopa; administer levodopa with a dopa-decarboxylase inhibitor to minimise interaction.
Action
Metadoxine enhances the elimination of alcohol from blood and tissues, which leads to faster recovery from alcohol intoxication. In the early stages of alcoholic liver disease, metadoxine has been suggested to prevent the redox imbalance of the hepatocytes and to prevent TNF-α induction.
Disclaimer: This information is independently developed by CIMS based on metadoxine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 CIMS. All rights reserved. Powered by CIMSAsia.com
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