Full Generic Medicine Info
Dosage/Direction for Use

Ocular hypertension, Open-angle glaucoma
Adult: As 0.1% or 0.3% drops: Instill 1 drop bid into the affected eye.
Bronchial asthma or history of bronchial asthma, severe COPD, symptomatic sinus bradycardia, 2nd or 3rd degree AV block, cardiogenic shock, overt cardiac failure.
Special Precautions
Patients w/ myasthenia gravis, a history of cardiac failure or psychiatric disease, DM, cerebrovascular insufficiency, peripheral vascular disease including Raynaud's syndrome. Avoid abrupt withdrawal in patients undergoing elective surgery. May mask certain signs and symptoms of hyperthyroidism. Pregnancy and lactation. Patient Counselling Metipranolol contains benzalkonium Cl which may be absorbed by soft contact lenses. Remove lens prior to admin and wait 15 min before reinserting.
Adverse Reactions
Transient local discomfort, abnormal vision, conjunctivitis, conjunctival leucoplakia, blepharitis, blurred vision, browache, oedema, eyelid dermatitis, photophobia, tearing, uveitis; hypersensitivity reaction, rash, angina, atrial fibrillation, MI, palpitation, bradycardia, anxiety, depression, HTN, dizziness, headache, nervousness, somnolence, asthenia, arthritis, myalgia, bronchitis, cough, dyspnoea, rhinitis, epistaxis, nausea.
Drug Interactions
Potential additive effects on systemic β-blockade w/ oral β-blockers. Possible additive hypotensive effects or bradycardia w/ catecholamine-depleting drugs (e.g. reserpine). Possible precipitation of left ventricular failure w/ Ca channel blockers. Concomitant use w/ digitalis and Ca channel blockers may prolong AV conduction time.
Metipranolol is a non-cardioselective β-blocker w/o significant intrinsic sympathomimetic activity and membrane-stabilising properties. It has weak local anaesthetic and myocardial depressant activity. It reduces intraocular pressure appears to be via decreased production of aqueous humour.
Onset: ≤30 min.
Duration: Intraocular pressure reduction: Up to 24 hr.
Ophthalmic: Store between 15-30°C.
CIMS Class
Antiglaucoma Preparations
ATC Classification
S01ED04 - metipranolol ; Belongs to the class of beta blocking agents. Used in the treatment of glaucoma.
Disclaimer: This information is independently developed by CIMS based on metipranolol from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 CIMS. All rights reserved. Powered by
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