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Indications/Uses
Moderate acute and chronic pain.
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Dosage/Direction for Use
Adult: PO Initial: 60 mg tid. Usual dose: 30-90 mg tid, adjusted according to patient's response.
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Administration
May be taken with or without food. May be taken w/ meals if GI discomfort occurs.
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Contraindications
History of convulsive disorders. Concomitant use w/ MAOI(s).
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Special Precautions
Patient w/ angle closure glaucoma, urinary retention, history of ischaemic heart disease. Hepatic and renal impairment. Elderly, childn. Pregnancy and lactation. Patient Counselling This drug may cause drowsiness, if affected, do not drive or operate machinery.
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Adverse Reactions
Significant: Sympathomimetic effect (e.g. tachycardia, aggravation or precipitation of angina). Rarely, pink discolouration of urine.
Nervous: Insomnia, drowsiness, dizziness, paraesthesia, tremor, lightheadedness, nervousness, confusion, hallucinations, headache, syncope, euphoria, convulsions.
CV: Hypotension, palpitations, tachycardia.
GI: Nausea, vomiting, dry mouth, abdominal pain, diarrhoea.
Genitourinary: Urinary retention.
Ophthalmologic: Blurred vision.
Dermatologic: Sweating, angioedema.
Immunologic: Hypersensitivity reactions (e.g. erythema multiforme, anaphylaxis).
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Drug Interactions
Increased risk of convulsion w/ TCA. Additive adverse effect w/ other antimuscarinic or sympathomimetic agents.
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CIMS Class
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ATC Classification
N02BG06 - nefopam ; Belongs to the class of other analgesics and antipyretics.
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