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Indications/Uses
Bacterial skin infections.
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Dosage/Direction for Use
Adult: Topical Per g cream contains neomycin 3,300 u and bacitracin Zn 250 u: Apply 3 times/day. Per g powd contains neomycin 5,000 u and bacitracin Zn 250 u: Apply 2-4 times/day.
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Contraindications
Hypersensitivity to aminoglycosides. Pre-existing nerve deafness. Neonates and infants <2 yr.
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Special Precautions
Neuromuscular disorders, hearing impaired, extensive skin damage. Avoid application in large quantities and prolonged use. Do not use if tympanic membrane is perforated. Pregnancy and lactation. Liver and renal impairment.
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Adverse Reactions
Hypersensitivity reactions. Possibility of ototoxicity and nephrotoxicity if used in large quantities or on large areas for prolonged use.
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Drug Interactions
Additive toxicity with neurotoxic, ototoxic or nephrotoxic drugs. Increased neuromuscular blockade and possibly respiratory depression with neuromuscular blocking agents if significant amount of neomycin is absorbed systemically.
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CIMS Class
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ATC Classification
A01AB08 - neomycin ; Belongs to the class of local antiinfective and antiseptic preparations. Used in the treatment of diseases of the mouth.
S03AA01 - neomycin ; Belongs to the class of antiinfectives used in ophthalmologic and otologic preparations. R02AB01 - neomycin ; Belongs to the class of antibiotics used in throat preparations. R02AB04 - bacitracin ; Belongs to the class of antibiotics used in throat preparations. J01GB05 - neomycin ; Belongs to the class of other aminoglycosides. Used in the systemic treatment of infections. A07AA01 - neomycin ; Belongs to the class of antibiotics. Used in the treatment of intestinal infections. D06AX04 - neomycin ; Belongs to the class of other topical antibiotics used in the treatment of dermatological diseases. B05CA09 - neomycin ; Belongs to the class of antiinfectives used as irrigating solutions. J01XX10 - bacitracin ; Belongs to the class of other antibacterials. Used in the systemic treatment of infections. S02AA07 - neomycin ; Belongs to the class of antiinfectives used in the treatment of ear infections. S01AA03 - neomycin ; Belongs to the class of antibiotics. Used in the treatment of eye infections. D06AX05 - bacitracin ; Belongs to the class of other topical antibiotics used in the treatment of dermatological diseases. |
