Nimorazole


Full Prescribing Info
Dosage/Direction for Use

Oral
Trichomoniasis
Adult: 2 g as a single dose. Alternatively, 1 g every 12 hr for 3 doses or 250 mg tid for 5-7 days. Sexual partners should be treated concomitantly.

Oral

Amoebiasis
Adult: 1 g bid for 5-10 days.

Oral

Giardiasis
Adult: 500 mg bid for 5-7 days.

Oral

Acute ulcerative gingivitis
Adult: 500 mg bid for 2 days.
Contraindications
Pregnancy and lactation.
Special Precautions
Blood dyscrasias; active disease of the CNS.
Adverse Reactions
Nausea, vomiting, diarrhoea, anorexia, epigastric pain, vertigo, somnolence, rash, pruritus.
Drug Interactions
Disulfiram-like reaction may occur with alcohol.
Action
Nimorazole is an antimicrobial with activity against anaerobic bacteria and protozoa. Its actions and properties are similar to metronidazole.
Absorption: Readily absorbed from the GI tract. Peak plasma levels within 2 hr.
Distribution: High levels reported to occur in salivary and vaginal secretions; distributes in breast milk.
Excretion: Via urine (as unchanged drug and 2 active metabolites).
ATC Classification
P01AB06 - nimorazole ; Belongs to the class of nitroimidazole derivatives antiprotozoals. Used in the treatment amoebiasis and other protozoal diseases.
Disclaimer: This information is independently developed by CIMS based on nimorazole from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 CIMS. All rights reserved. Powered by CIMSAsia.com
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