Olmesartan


Concise Prescribing Info
Indications/Uses
HTN.
Dosage/Direction for Use
Adult: PO Initial: 10-20 mg once daily, may be increased to max 40 mg once daily if needed.
Contraindications
Biliary obstruction. Pregnancy.
Special Precautions
Patients w/ aortic or mitral valve stenosis, renal artery stenosis; at risk for hypotension (e.g. patients w/ volume or salt depletion); history of angioedema; at risk for hyperkalaemia (e.g. patients w/ DM). Severe renal and hepatic impairment. Lactation. Monitoring Parameters Monitor BP, serum creatinine and K levels periodically.
Adverse Reactions
May cause sprue-like enteropathy (Symptoms: Severe, chronic diarrhoea w/ substantial wt loss). Dizziness, headache, abdominal pain, dyspepsia, diarrhoea, gastroenteritis, nausea, bronchitis, pharyngitis, rhinitis, arthritis, back pain, skeletal pain, fatigue, flu-like symptoms, angioedema, peripheral oedema, haematuria, UTI, hyperkalaemia, hypertriglyceridemia, hyperuricaemia, hyperglycaemia, elevated liver enzymes.
Potentially Fatal: Acute renal failure.
Drug Interactions
Increased risk of hyperkalaemia w/ ACE inhibitors, K-sparing diuretics, K salts or K supplements and drugs that may increase serum K (e.g. ciclosporin, eplerenone). May potentiate BP lowering effects w/ other antihypertensives. May decrease glomerular filtration w/ NSAIDs which can cause acute renal failure. May increase serum concentrations and toxicity of lithium.
Disclaimer: This information is independently developed by CIMS based on olmesartan from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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