Generic Medicine Info
Should be taken with food.
Hypersensitivity to olsalazine or other salicylates.
Special Precautions
Patient w/ asthma, severe allergies. Renal and hepatic impairment. Pregnancy and lactation. Patient Counselling This drug may cause dizziness and/or blurred vision, if affected, do not drive or operate machinery. Monitoring Parameters Monitor renal function (e.g. serum creatinine, BUN, urinalysis) prior and during treatment (every 3 mth for 1 yr, then every 6 mth for next 4 yr, then annually thereafter). Monitor CBC, LFT, stool frequency.
Adverse Reactions
Significant: Diarrhoea, ulcerative colitis symptoms exacerbation. Rarely, blood dyscrasias. Nervous: Headache, dizziness, paraesthesia, depression, vertigo, fatigue, drowsiness, lethargy. CV: Tachycardia. GI: Nausea, vomiting, dyspepsia, abdominal cramps and pain, bloating, stomatitis, anorexia. Resp: Upper resp tract infection, dyspnoea. Hepatic: Increased hepatic enzyme. Haematologic: Thrombocytopenia. Musculoskeletal: Arthralgia, myalgia. Dermatologic: Rash, pruritus, alopecia, photosensitivity reaction, urticaria. Others: Pyrexia.
Potentially Fatal: Liver necrosis, liver failure.
Drug Interactions
Increased risk of bleeding (e.g. haematoma) w/ LMWH or heparinoids. Increased prothrombin time w/ warfarin. Increased risk of myelosuppression w/ 6-mercaptopurine and thioguanine. Increased risk of developing Reye's syndrome w/ varicella vaccine, avoid admin w/in 6 wk of vaccination.
ATC Classification
A07EC03 - olsalazine ; Belongs to the class of aminosalicylic acid and similar antiinflammatory. Used in the treatment of intestinal inflammation.
Disclaimer: This information is independently developed by CIMS based on olsalazine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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