Oxomemazine


Full Prescribing Info
Dosage/Direction for Use

Oral
Pruritic skin disorders, Hypersensitivity reactions
Adult: 5-13 mg daily in divided doses.
Child: 0-3 mth: 2.5-5 mg/day; >3 mth: 5-20 mg/day. Doses to be taken in 2-3 divided doses.
Contraindications
Prostatic adenoma, angle-closure glaucoma, paralytic ileus, pyloric stenosis, myasthenia, status asthmaticus, COPD.
Special Precautions
May impair ability to drive or operate machinery. Renal and hepatic impairment. Pregnancy and lactation. Children <1 yr. Elderly.
Adverse Reactions
Gynaecomastia, rash, photosensitivity, urinary retention, dry mouth, constipation, orofacial dyskinesia, somnolence, headache, vertigo, muscular hyptonia.
Drug Interactions
Additive CNS depression with alcohol, barbiturates, hypnotics, opioid analgesics, anxiolytic sedatives.
Lab Interference
May interfere with skin testing.
Action
Oxomemazine, a phenothiazine derivative, is a sedating antihistamine. It competitively binds to histamine (H1) receptors, resulting in inhibition of the pharmacological effects of histamines. It also has some sedative, anticholinergic and antiserotoninergic effects.
ATC Classification
R06AD08 - oxomemazine ; Belongs to the class of phenothiazine derivatives used as systemic antihistamines.
Disclaimer: This information is independently developed by CIMS based on oxomemazine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 CIMS. All rights reserved. Powered by CIMSAsia.com
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