Pentosan polysulfate sodium

Generic Medicine Info
Should be taken on an empty stomach. Take at least 1 hr before or 2 hr after meals.
Special Precautions
Patient w/ signs/symptoms of coagulopathy, bleeding disorder (e.g. haemophilia, thrombocytopenia), aneurysm, GI disease (e.g. GI ulcerations, diverticula, polyps), heparin-induced thrombocytopenia; to undergo invasive procedures. Hepatic impairment. Pregnancy and lactation. Monitoring Parameters Monitor CBC, aPTT, prothrombin time, serum Ca, LFT, renal function tests.
Adverse Reactions
Significant: Rectal haemorrhage, bleeding complications (e.g. ecchymosis, epistaxis, gum haemorrhage), alopecia; abnormal LFT. Nervous: Headache, dizziness, insomnia, depression, hyperkinesia. GI: Diarrhoea, nausea, abdominal pain, dyspepsia, vomiting, mouth ulcer, colitis, esophagitis, flatulence, constipation, anorexia. Resp: Pharyngitis, rhinitis, dyspnoea. Dermatologic: Skin rash, pruritus, urticaria.
Drug Interactions
Increased risk of bleeding w/ oral anticoagulants, heparin, NSAIDs, streptokinase, tissue plasminogen activator.
ATC Classification
G04BX15 - pentosan polysulfate sodium ; Belongs to the class of other urologicals.
C05BA04 - pentosan polysulfate sodium ; Belongs to the class of heparins or heparinoids used topically in antivaricose therapy.
Disclaimer: This information is independently developed by CIMS based on pentosan polysulfate sodium from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in