Polymyxin b + neomycin + hydrocortisone


Generic Medicine Info
Contraindications
Hypersensitivity to polymyxin B, neomycin and hydrocortisone and other aminoglycosides. Perforated tympanic membrane, untreated viral, fungal and tubercular infections. Children <3 years.
Special Precautions
Patient with conditions where significant systemic absorption may occur, venous stasis eczema and ulceration, pre- and post-operative period. Prolonged use. Children. Pregnancy and lactation.
Adverse Reactions
Significant: Irreversible ototoxicity (e.g. deafness), nephrotoxicity, neurotoxicity, neomycin sensitisation (e.g. itching, reddening, oedema, failure to heal), immunosuppression, Kaposi sarcoma, and suppression of the pituitary-adrenal (HPA) axis after systemic absorption. Ear and labyrinth disorders: Stinging, burning sensation in ears.
Potentially Fatal: Pseudomembranous colitis.
Drug Interactions
Neomycin and polymyxin may increase risk of respiratory depression with neuromuscular blocking agents.
ATC Classification
A01AC03 - hydrocortisone ; Belongs to the class of local corticosteroid preparations. Used in the treatment of diseases of the mouth.
D07AA02 - hydrocortisone ; Belongs to the class of weak (group I) corticosteroids. Used in the treatment of dermatological diseases.
A07AA05 - polymyxin B ; Belongs to the class of antibiotics. Used in the treatment of intestinal infections.
S03AA03 - polymyxin B ; Belongs to the class of antiinfectives used in ophthalmologic and otologic preparations.
A07EA02 - hydrocortisone ; Belongs to the class of corticosteroids acting locally. Used in the treatment of intestinal inflammation.
A01AB08 - neomycin ; Belongs to the class of local antiinfective and antiseptic preparations. Used in the treatment of diseases of the mouth.
S03AA01 - neomycin ; Belongs to the class of antiinfectives used in ophthalmologic and otologic preparations.
S02BA01 - hydrocortisone ; Belongs to the class of corticosteroids used in the treatment of inflammation of the ear.
R02AB01 - neomycin ; Belongs to the class of antibiotics used in throat preparations.
J01GB05 - neomycin ; Belongs to the class of other aminoglycosides. Used in the systemic treatment of infections.
C05AA01 - hydrocortisone ; Belongs to the class of products containing corticosteroids for topical use. Used in the treatment of hemorrhoids and anal fissures.
S01BA02 - hydrocortisone ; Belongs to the class of corticosteroids. Used in the treatment of inflammation of the eye.
A07AA01 - neomycin ; Belongs to the class of antibiotics. Used in the treatment of intestinal infections.
D07XA01 - hydrocortisone ; Belongs to the class of weak (group I) corticosteroids in other combinations. Used in the treatment of dermatological diseases.
B05CA09 - neomycin ; Belongs to the class of antiinfectives used as irrigating solutions.
D06AX04 - neomycin ; Belongs to the class of other topical antibiotics used in the treatment of dermatological diseases.
S02AA11 - polymyxin B ; Belongs to the class of antiinfectives used in the treatment of ear infections.
S02AA07 - neomycin ; Belongs to the class of antiinfectives used in the treatment of ear infections.
S01CB03 - hydrocortisone ; Belongs to the class of corticosteroids/antiinfectives/mydriatics combinations. Used in the treatment of eye diseases.
S01AA03 - neomycin ; Belongs to the class of antibiotics. Used in the treatment of eye infections.
S01AA18 - polymyxin B ; Belongs to the class of antibiotics. Used in the treatment of eye infections.
H02AB09 - hydrocortisone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
J01XB02 - polymyxin B ; Belongs to the class of polymyxins. Used in the systemic treatment of infections.
Disclaimer: This information is independently developed by CIMS based on polymyxin b + neomycin + hydrocortisone from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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