Povidone iodine

Mouth/Throat
Oral hygiene
Adult: As 1% solution: Rinse or gargle 10 mL undiluted solution with an equal volume of warm water for 30 seconds 4 times daily for up to 14 days, or as directed.
Child: As 1% solution: >6 years Same as adult dose.

Mouth/Throat
Mouth and throat infections
Adult: As 1% solution: Rinse or gargle 10 mL undiluted solution with an equal volume of warm water for 30 seconds 4 times daily for up to 14 days, or as directed.
Child: As 1% solution: >6 years Same as adult dose.

Ophthalmic
Prophylaxis of ocular infection following surgical procedures
Adult: As 5% solution: Instill 2-3 drops onto affected eye(s), leave for 2 minutes then rinse off with 0.9% Na chloride solution.

Topical/Cutaneous
As an antiseptic agent
Adult: As 5-10% solution, 10% gel, 10% ointment, or 10 % aerosol spray: Apply as directed.
Child: As 5-10% solution, 10% gel or 10% ointment: Same as adult dose. As 10% aerosol spray: ≥2 years Same as adult dose.
Incompatibility: May cause bubbly brown explosion with hydrogen peroxide solution.

Topical/Cutaneous
Acne vulgaris
Adult: As 4% solution: Apply bid directly or with moistened sponge unto affected area, leave for 3-5 minutes then rinse off with water.
Child: As 4% solution: >2 years Same as adult dose.
Incompatibility: May cause bubbly brown explosion with hydrogen peroxide solution.

Vaginal
Vaginal irritation
Adult: As 0.3% douche: Insert 0.3% solution once daily for 5-7 days.

Topical/Cutaneous
Pyoderma
Adult: As 4% shampoo: Apply 2-3 capfuls in wet scalp, rinse and repeat application, lather with a warm water. Repeat procedure once weekly until desired improvement achieved.
Child: As 4% shampoo: 2-12 years Apply 1-2 capfuls in wet scalp, rinse and repeat application, lather with a warm water. Repeat procedure once weekly until desired improvement achieved. >12 years Same as adult dose.
Incompatibility: May cause bubbly brown explosion with hydrogen peroxide solution.

Topical/Cutaneous
Seborrhoeic dermatitis
Adult: As 4% shampoo: Apply 2-3 capfuls in wet scalp, rinse and repeat application, lather with a warm water. Repeat procedure once weekly until desired improvement achieved.
Child: As 4% shampoo: 2-12 years Apply 1-2 capfuls in wet scalp, rinse and repeat application, lather with a warm water. Repeat procedure once weekly until desired improvement achieved. >12 years Same as adult dose.
Incompatibility: May cause bubbly brown explosion with hydrogen peroxide solution.

History of abnormal thyroid function or goitre (e.g. nodular colloid goitre, endemic goitre, Hashimoto's thyroiditis).

Patient with serious wounds including burns. Renal impairment. Children. Pregnancy and lactation.

Significant: Hypo- or hyper-thyroidism (long-term). Rarely, hypersensitivity reactions; conjunctival hyperaemia, superficial punctuate keratitis, cytotoxicity (ophth). Dermatologic: Rarely, local irritation, pruritus, rash, oedema, burns.

May increase risk of thyroid-related reactions with lithium. Risk of formation of caustic compounds with ophthalmic formulations containing Hg-based preservatives.

May interfere with thyroid function tests. False-positive result with contaminated povidone iodine for the detection of occult blood in stool or blood in urine.

Povidone iodine is an iodophore that has a broad-spectrum germicidal activity against a wide range of bacteria, viruses, fungi, protozoa and spores. It is a complex of polyvinylpyrrolidone (povidone) with iodine. After application, it gradually and continuously delivers iodine to exert its germicidal activity.
Absorption: Absorbed from skin, vaginal mucosa.
Distribution: Crosses the placenta and enters breast milk.
Excretion: Mainly via urine.

Mouth/Throat: Store below 25°C. Protect from light. Ophthalmic: Store below 25°C. Protect from light. Topical/Cutaneous: Store below 25°C. Protect from light. Vaginal: Store below 25°C. Protect from light.

Mouth/Throat Preparations / Other Eye Preparations / Psoriasis, Seborrhea & Ichthyosis Preparations / Skin Antiseptics & Disinfectants / Acne Treatment Preparations / Preparations for Vaginal Conditions

D09AA09 - povidone-iodine ; Belongs to the class of ointment dressings with antiinfectives.
R02AA15 - povidone-iodine ; Belongs to the class of antiseptics used in throat preparations.
S01AX18 - povidone-iodine ; Belongs to the class of other antiinfectives. Used in the treatment of eye infections.
D11AC06 - povidone-iodine ; Belongs to the class of medicated shampoos.
D08AG02 - povidone-iodine ; Belongs to the class of iodine product antiseptics. Used in the treatment of dermatological diseases.
G01AX11 - povidone-iodine ; Belongs to the class of other antiinfectives and antiseptics. Used in the treatment of gynecological infections.