Generic Medicine Info
Hypersensitivity. G6PD deficiency, and other cellular metabolic disorders causing haemolytic anaemia.
Special Precautions
Patients with history of atopic allergies. Children. Pregnancy and lactation. Monitoring Parameters Perform G6PD deficiency screening prior to initiation of therapy. Monitor plasma uric acid levels 4 hours after administration then every 6-8 hours until tumour lysis syndrome resolution; CBC. Monitor for signs and symptoms of hypersensitivity reactions.
Adverse Reactions
Significant: Severe haemolytic reactions, methaemoglobinaemia. Gastrointestinal disorders: Diarrhoea, vomiting, nausea, abdominal pain, constipation, mucositis. General disorders and administration site conditions: Fever. Hepatobiliary disorders: Hyperbilirubinemia, increased serum ALT. Infections and infestations: Sepsis. Immune system disorders: IgG and IgE antibody development. Nervous system disorders: Headache. Metabolism and nutrition disorders: Peripheral oedema, hypophosphataemia, hypervolaemia. Psychiatric disorders: Anxiety. Respiratory, thoracic and mediastinal disorders: Pharyngolaryngeal pain.
Potentially Fatal: Serious hypersensitivity reactions (e.g. anaphylactic shock).
ATC Classification
V03AF07 - rasburicase ; Belongs to the class of detoxifying agents used in antineoplastic treatment.
Disclaimer: This information is independently developed by CIMS based on rasburicase from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in