Salbutamol + theophylline


Concise Prescribing Info
Indications/Uses
Listed in Dosage.
Dosage/Direction for Use
Adult: PO Bronchial asthma; Chronic bronchitis; Emphysema Per tab contains salbutamol 2 mg and theophylline 100 mg: 1-2 tab 3-4 times/day.
Contraindications
Hypersensitivity, thyrotoxicosis.
Special Precautions
Hepatic impairment, cardiac failure, hypertension, arrhythmias, pulmonary oedema, hyperthyroidism, diabetes mellitus, history of peptic ulcer and convulsive disorders, patients on MAOIs or tricyclic antidepressants, high fever, neonates and infants, pregnancy, lactation.
Adverse Reactions
Seizures, tremor, muscle cramps, palpitation, hypokalaemia, headache, anorexia, nausea, anxiety, irritability, insomnia, rarely rash and angioedema.
Potentially Fatal: Arrhythmias including premature ventricular contractions.
Drug Interactions
Increased theophylline toxicity with propranolol, cimetidine, erythromycin (7-5 days), quinolone antibiotics. Reduced efficacy with rifampicin, phenobarbitone, phenytoin, carbamazepine, sulfinpyrazone and smoking. Increased risk of hypokalaemia with diuretics.
ATC Classification
R03DA04 - theophylline ; Belongs to the class of xanthines. Used in the systemic treatment of obstructive airway diseases.
R03AC02 - salbutamol ; Belongs to the class of adrenergic inhalants, selective beta-2-adrenoreceptor agonists. Used in the treatment of obstructive airway diseases.
R03CC02 - salbutamol ; Belongs to the class of adrenergics for systemic use, selective beta-2-adrenoreceptor agonists. Used in the treatment of obstructive airway diseases.
Disclaimer: This information is independently developed by CIMS based on salbutamol + theophylline from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 CIMS. All rights reserved. Powered by CIMSAsia.com
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