Sulfaguanidine


Generic Medicine Info
Contraindications
Porphyria; severe renal or hepatic failure; blood disorders; hypersensitivity to sulfonamides; SLE. Pregnancy (prior to delivery). Lactation. Infants within 1-2 mth of birth.
Special Precautions
Adequate fluid intake is necessary to reduce the risk of crystalluria. Discontinue immediately if rash appears. Renal or hepatic impairment; asthma or history of allergy; elderly. G6PD deficiency.
Adverse Reactions
GI effects, hypersensitivity reactions, nephrotoxic reactions, hepatic disorders, CV effects, hypoglycaemia, hypothyroidism, neurological reactions. Pseudomembranous colitis; jaundice and kernicterus in the newborn.
Potentially Fatal: Toxic epidermal necrolysis, Stevens-Johnson syndrome, anaphylaxis, blood dyscrasias.
Drug Interactions
Action antagonised by PABA and procaine group of local anaesthetics. Potentiates oral anticoagulants, methotrexate and phenytoin. Increased risk of crystalluria with compounds that render urine acidic.
CIMS Class
ATC Classification
A07AB03 - sulfaguanidine ; Belongs to the class of sulfonamide antiinfectives. Used in the treatment of intestinal infections.
Disclaimer: This information is independently developed by CIMS based on sulfaguanidine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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