Sulfamethoxazole


Generic Medicine Info
Administration
Should be taken on an empty stomach (i.e. At least one hour before food or two hours after food).
Contraindications
Severe renal or hepatic impairment, blood disorders, hypersensitivity to sulfonamides, porphyria, SLE, infants <2 mth, pregnancy (3rd trimester) and lactation.
Special Precautions
Renal or hepatic impairment, history of allergy or asthma, AIDS, G6PD deficiency, elderly, ensure adequate fluid intake to reduce risk of crystalluria. Pregnancy.
Adverse Reactions
Nausea, vomiting, anorexia, diarrhoea, hypersensitivity reactions, blood disorders, serum sickness-like syndrome, hypoglycaemia, hypothyroidism, pseudomembranous colitis, kernicterus in premature neonates.
ROUTE(S) : PO: B D if administered near term.
ROUTE(S) : IV / Parenteral: D
Drug Interactions
Concurrent use increases phenytoin and methotrexate levels; increased risk of bleeding with warfarin and acenocoumarol; may potentiate antidiabetic effect of sulphonylureas.
CIMS Class
ATC Classification
J01EC01 - sulfamethoxazole ; Belongs to the class of intermediate-acting sulfonamides. Used in the systemic treatment of infections.
Disclaimer: This information is independently developed by CIMS based on sulfamethoxazole from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 CIMS. All rights reserved. Powered by CIMSAsia.com
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