Trimetazidine


Concise Prescribing Info
Indications/Uses
Stable angina.
Dosage/Direction for Use
Adult: PO As adjunctive therapy for symptomatic treatment in patients who are inadequately controlled by or intolerant to first-line antianginal therapies: Conventional tab: 20 mg tid. Modified-release tab: 35 mg bid.
Administration
Should be taken with food.
Contraindications
Parkinson's disease, parkinsonian symptoms, tremors, restless leg syndrome and other movement related disorders. Severe renal impairment (CrCl <30 mL/min). Lactation.
Special Precautions
Moderate renal impairment. Elderly. Pregnancy. Not indicated for initial treatment of unstable angina, myocardial infarction nor in the pre-hospital phase or during the first days of hospitalisation. Patient Counselling This drug may cause dizziness and drowsiness, if affected, do not drive or operate machinery.
Adverse Reactions
Significant: Movement disorders (e.g. Parkinsonian symptoms, restless leg syndrome, tremors, gait instability). Gastrointestinal disorders: Abdominal pain, dyspepsia, diarrhoea, nausea, vomiting. General disorders and administration site conditions: Asthenia. Skin and subcutaneous tissue disorders: Rash, pruritus, urticaria. Vascular disorders: Rarely, arterial hypotension, orthostatic hypotension.
CIMS Class
ATC Classification
C01EB15 - trimetazidine ; Belongs to the class of other cardiac preparations.
Disclaimer: This information is independently developed by CIMS based on trimetazidine from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to CIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, CIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 CIMS. All rights reserved. Powered by CIMSAsia.com
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in