Abilify Discmelt

Abilify Discmelt

aripiprazole

Manufacturer:

Otsuka
Concise Prescribing Info
Contents
Aripiprazole
Indications/Uses
Acute treatment of schizophrenia for adult & adolescent. Maintenance treatment in adults w/ schizophrenia & bipolar disorder. Acute mania & mixed episodes of bipolar disorder in childn, adolescent & adult. Adjunctive therapy for major depressive disorder.
Dosage/Direction for Use
Schizophrenia Adult 10 or 15 mg once daily. Adolescent 13-17 yr Initially 2 mg/day then, titrated to 5 mg/day followed by a target dose of 10 mg/day. Doses are titrated in a 2-day interval. Bipolar disorder Adult 30 mg once daily. Childn & adolescent 10-17 yr Initially 2 mg/day then, titrated to 5 mg/day followed by a target dose of 10 mg/day. Doses are titrated in a 2-day interval. Adjunctive treatment for patients taking antidepressants 2-5 mg/day. Adjunctive therapy for major depressive disorder 2-15 mg/day. Adjust dose gradually up to 5 mg/day at not <1-wk interval.
Administration
May be taken with or without food.
Special Precautions
Reduce dose or discontinue if signs or symptoms of tardive dyskinesia & neuroleptic malignant syndrome appear. Patient w/ history of seizure. May impair ability to drive or operate machinery. Pregnancy & lactation.
Adverse Reactions
Headache, nausea, vomiting, constipation, anxiety, insomnia, lightheadedness, somnolence, akathisia, dyspepsia, agitation.
Drug Interactions
Increased clearance & lower blood levels w/ CYP3A4 inducers eg, carbamazepine. Inhibit elimination & increased blood levels w/ CYP3A4 inhibitors eg, ketoconazole & CYP2D6 inhibitors eg, quinidine, fluoxetine or paroxetine.
MIMS Class
ATC Classification
N05AX12 - aripiprazole ; Belongs to the class of other antipsychotics.
Presentation/Packing
Form
Abilify Discmelt orally disintegrating tab 15 mg
Packing/Price
1 × 10's
Form
Abilify Discmelt orally disintegrating tab 10 mg
Packing/Price
1 × 10's
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