Each 2 mL injection contains amikacin sulfate 250 or 500 mg.
Each 4 mL injection contains amikacin sulfate 1 g.
Short-term therapy for serious infections due to amikacin-sensitive organisms.
IM Injection: Neonates: Initially 10 mg/kg/day followed by 7.5 mg/kg per 12 hrs. Maximum Total Daily Dose: 15 mg/kg/day or 1.5 g/day. Duration of Therapy: 7-10 days. IV Infusion: 500 mg in 100-200 mL of 0.9% NaCl or 5% Dextrose solution to be given within 30-60 min (in adults and children) or 1-2 hrs (in infants).
Hypersensitivity to amikacin and other aminoglycosides.
Patients with impaired kidney function.
Dosage should be adjusted or discontinued if vestibular or hearing disturbances occur.
Avoid prolonged use.
Use in pregnancy and lactation: Amiosin injection is not recommended in pregnant and lactating women.
Neurotoxicity, ototoxicity, nephrotoxicity; skin rash, drug fever, headache, paresthesia, tremor, nausea and vomiting, eosinophilia, arthralgia, anemia, hypotension; acute muscular paralysis, apnea.
Gentamycin, tobramycin, neomycin, streptomycin, cephaloridine, polymixin B, cholistin, potent diuretic agents (ethacrynic acid, furosemide, mannitol).
J01GB06 - amikacin ; Belongs to the class of other aminoglycosides. Used in the systemic treatment of infections.
Inj (vial) 250 mg/2 mL x 2 mL x 5's. 500 mg/2 mL x 2 mL x 5's. 1 g/4 mL x 4 mL x 5's.