Amiosin

Amiosin

amikacin

Manufacturer:

Dexa Medica
Full Prescribing Info
Contents
Amikacin sulfate.
Description
Each 2 mL injection contains amikacin sulfate 250 or 500 mg.
Each 4 mL injection contains amikacin sulfate 1 g.
Indications/Uses
Short-term therapy for serious infections due to amikacin-sensitive organisms.
Dosage/Direction for Use
IM Injection: Neonates: Initially 10 mg/kg/day followed by 7.5 mg/kg per 12 hrs. Maximum Total Daily Dose: 15 mg/kg/day or 1.5 g/day. Duration of Therapy: 7-10 days. IV Infusion: 500 mg in 100-200 mL of 0.9% NaCl or 5% Dextrose solution to be given within 30-60 min (in adults and children) or 1-2 hrs (in infants).
Contraindications
Hypersensitivity to amikacin and other aminoglycosides.
Special Precautions
Patients with impaired kidney function.
Dosage should be adjusted or discontinued if vestibular or hearing disturbances occur.
Avoid prolonged use.
Use in pregnancy and lactation: Amiosin injection is not recommended in pregnant and lactating women.
Adverse Reactions
Neurotoxicity, ototoxicity, nephrotoxicity; skin rash, drug fever, headache, paresthesia, tremor, nausea and vomiting, eosinophilia, arthralgia, anemia, hypotension; acute muscular paralysis, apnea.
Drug Interactions
Gentamycin, tobramycin, neomycin, streptomycin, cephaloridine, polymixin B, cholistin, potent diuretic agents (ethacrynic acid, furosemide, mannitol).
MIMS Class
ATC Classification
J01GB06 - amikacin ; Belongs to the class of other aminoglycosides. Used in the systemic treatment of infections.
Presentation/Packing
Inj (vial) 250 mg/2 mL x 2 mL x 5's. 500 mg/2 mL x 2 mL x 5's. 1 g/4 mL x 4 mL x 5's.
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